Determination of Glycan structure use MS/MS

Presentation in Nov 19

Determination of Glycan structure use MS

After presentation, Prof. Memo give me some advise. I will modify and upload it.

• Slides modify

Title: Determination of N-Glycan structure use MS/MS

isomeric molecules isoform

De novo De novo

biology biological

• Problem

Why my problem is NP-Hard?

Because the glycan structures is diverse, the number of candidate glycan structures is huge.

• Comment

The 10/20/30 Rule of PowerPoint by Guy Kawasaki

NP-Hard(Non-deterministic Polynomial-time Hard)=非確定性多項式

Reorganization

1. Why glycan is important?
2. The differences between N-glycan and O-glycan
3. Explain the problem more specific.  (Search space is some large, accuracy is not good.)
4. Explain the MS, CID, and HCD.
5. Previous work
6. How to improve ?
7. How to measure the success?

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