Worlds within worlds: evolution of the vertebrate gut microbiota
Ruth E. Ley, et al., Nature Reviews Microbiology
Continue reading Worlds within worlds: evolution of the vertebrate gut microbiota
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Here is the new MultiNGlycan website. Previous one is ugly and I don’t like it. I world like to publish a poster in 2010. I wrote a abstract on my capstone project. After my Prof. Tang revise my abstract, it seem more clear than I wrote before. I want to improve my English writing, any idea? This paper try to use microarray technique applied to carbohydrate analysis. Firstly, they need to know if the glycoconjugates can be immobilized on the microarray surface. Secondly, if it can be immobilized, will it have the same properties or not. Thirdly, is the sensitivity can be use in the clinical sample. Finally, is this microarray can be another tool for carbohydrate-mediated molecular recognition discovery. This paper talks about how to use Globo H antigen as a breast cancer biomarker. Globo H which is a hexasaccharide and belongs to antigenic carbohydrates is highly expressed on some cancers cell surface. Breast cancer patients have highly expression antibodies against the Globo H epitope. They used Mbr1 and VK9 antibodies which can specific recognize Globo H epitope. Use these two findings they can specific differentiate health and cancer sample. They use glycan microarray to assay the finding. Complexities and algorithms for glycan structure sequencing using tandem mass spectrometry Determination of Glycan Structure from Tandem Mass Spectra Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and [...] |
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